UBXN1 anticorps (AA 50-100)

N° du produit ABIN7450872

Cet anticorps anti-UBXN1 est un anticorps Lapin Polyclonal détectant UBXN1 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour UBXN1 anticorps (AA 50-100) (ABIN7450872)

Antigène: UBXN1 (UBX Domain Protein 1 (UBXN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBXN1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-UBXN1 anticorps

Épitope: AA 50-100

Fonction: Rabbit anti-UBXN1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 50 and 100

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur UBXN1

Antigène: UBXN1 (UBX Domain Protein 1 (UBXN1))

Autre désignation: UBXN1

Sujet: Background: UBX domain-containing protein 1 (UBXN1) is a ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. The interaction between UBXN1 and autoubiquitinated BRCA1, leads to the inhibition the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. UBXN1 is also a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.3 kDa protein, UBXD10, 2B28, and SAKS1.

ID gène: 51035

NCBI Accession: NP_056937

UniProt: Q04323